| Guard Scorpion | Mako Reactor No. 1 | Attack with lightning; heal or wait when its tail rises. | Attacking while raised triggers a Tail Laser counter. |
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| Air Buster | Mako Reactor No. 5 | Use lightning and attacks from behind. | Keep someone ready to heal against counters after attacking from behind. |
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| Aps | Sewer | Weak to fire. Attack with Fire and heal the party after its wave attack. | The wave also hits the enemy itself. Prioritize your own healing. |
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| Reno | Sector 7 pillar | Attack Pyramids to free companions. | Break them before everyone is trapped. |
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| Sample:H0512 | Shinra Building | Target the main enemy and retain poison-healing options. | Do not keep killing only the accompanying enemies. |
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| Hundred Gunner／Heli Gunner | Shinra Building elevator | Use Barret's ranged weapon or lightning magic. | Aerith and others' close-range attacks may not reach. |
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| Rufus／Dark Nation | Shinra Building roof | Heal with Cloud alone and defeat the support-using dog first. | Do not give all healing materia to the other party. |
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| Motor Ball | Escape from Midgar | Use lightning and maintain the party's HP. | Expect fire attacks. Check HP after the escape minigame. |
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| Bottomswell | Under Junon | Use magic or ranged attacks against the floating main enemy. | Free an ally trapped in a water sphere by casting non-Bio magic, such as Fire, on the sphere. |
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| Jenova・BIRTH | Transport ship | Spread healing across several characters because Stop can disable a healer. | Pick up Ifrit after battle before leaving the room. |
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| Dyne | Corel Prison | Prepare healing and a weapon for Barret alone. | You cannot fight with healing roles spread across a three-person party. |
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| Gi Nattak | Cave of the Gi | Using an X-Potion on the main enemy is an option. | An undead enemy defeatable through healing effects. Finish pickups first. |
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| Materia Keeper | Mt. Nibel | Avoid fire and prepare party-wide healing and lightning protection. | To learn Trine, have its equipped character take it before killing the enemy. |
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| Palmer | Rocket Town | Keep healing, defeat him and continue to the plane event. | Prepare for the gun's elemental attacks. |
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| Red Dragon | Temple of the Ancients | Avoid feeding its fire absorption; use physical or other-element attacks. | Check that you collect Bahamut immediately after battle. |
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| Demons Gate | Temple exit | Reduce physical attacks with the back row and Barrier, and attack with Limits or other tools. | Change Aerith's rare equipment before battle. |
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| Jenova・LIFE | Forgotten Capital | Use a Water Ring or similar water protection. | Keep someone who nullifies or absorbs water available to heal. |
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| Twin Head | Gaia's Cliff | Use ice on the fire head and fire on the ice head. | Heal in preparation for the party-wide attack immediately after each head dies. |
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| Jenova・DEATH | Whirlwind Maze | Prepare fire resistance and protection against silencing the healer. | Check pre-Meteor pickups first. |
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| Ultima Weapon | Mideel | Heal after party-wide attacks and continue until the battle ends. | This is not the battle that awards Cloud's ultimate weapon. |
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| Carry Armor | Underwater Reactor | Use lightning to remove arms, free captured characters and reach the main body. | Damage to an arm also reaches its captive. Prepare MBarrier and party-wide healing. |
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| Rude | Rocket launch pad | Reduce the soldiers; steal Ziedrich before killing him if pursuing it. | Heal before entering the rocket code. |
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| Three Turks | Return to Midgar | If fighting, check steals, statuses and elemental absorption. | Depending on Wutai progression, an option to avoid the battle may be available. |
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| Proud Clad | Mako Cannon | Remove the part applying Reflect and prepare healing after party-wide attacks. | Check before casting healing magic on someone with Reflect. Bring Barret to the next stairs. |
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| Hojo | Mako Cannon | Prioritize the main enemy over the capsule's companions. | Defeating him does not end the consecutive battles. |
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| Heretic Hojo | Mako Cannon | Attack the main body and restore HP lost to arm attacks. | Save MP for healing and status cures in the third stage. |
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| Ultimate Lifeform Hojo NA | Mako Cannon | Use prevention such as Ribbon and cures against consecutive attacks and statuses. | If the controllable healer is disabled, have someone else use an item. |
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| Jenova・SYNTHESIS | Northern Crater | Check HP around the start of the countdown and attack the main body. | Save party-wide healing for Ultima after the countdown. |
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| Reverse Sephiroth | Northern Crater | Watch body-part revival and core status to progress toward the main body. | The number of parties can vary. Prepare equipment for the other parties too. |
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| Safer Sephiroth | Northern Crater | Restore HP and statuses after party-wide attacks, then resume attacking. | No fixed HP or guaranteed winning setup is asserted. |
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